Warning: require_once(D:\SERVER\htdocs/includes/defines.php): failed to open stream: No such file or directory in D:\SERVER\htdocs\index.php on line 38

Fatal error: require_once(): Failed opening required 'D:\SERVER\htdocs/includes/defines.php' (include_path='D:\SERVER\php\PEAR') in D:\SERVER\htdocs\index.php on line 38